Sad face! So I guess the conundrum that is history’s most intriguing smile has been solved: “The Italian scientist says the model in the oil painting had a xanthelasma – a subcutaneous accumulation of cholesterol – in the hollow of her left eye and a fatty tissue tumour. It suggests very high levels of cholesterol in the model, thought to be Lisa del Giocondo, a member of a Florence family who married a cloth and silk merchant.”
I feel her pain having high cholesterol my entire life. Though in my defense I did eat a bowl of ice cream a night from the time I was seven until I turned 15.